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Sergey Orlov Selected Research

FP-1039

1/2020A phase Ib study of GSK3052230, an FGF ligand trap in combination with pemetrexed and cisplatin in patients with malignant pleural mesothelioma.
10/2019An open-label phase IB study to evaluate GSK3052230 in combination with paclitaxel and carboplatin, or docetaxel, in FGFR1-amplified non-small cell lung cancer.

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Sergey Orlov Research Topics

Disease

16Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2022 - 08/2011
7Neoplasms (Cancer)
01/2020 - 04/2014
5Brain Neoplasms (Brain Tumor)
01/2022 - 02/2014
5Disease Progression
01/2020 - 02/2014
5Neutropenia
10/2019 - 02/2015
3Nausea
10/2019 - 09/2013
3Diarrhea
10/2019 - 09/2013
2Hyperphosphatemia
01/2020 - 10/2019
2Lung Neoplasms (Lung Cancer)
01/2020 - 01/2017
2Thrombocytopenia (Thrombopenia)
11/2017 - 12/2015
2Vomiting
01/2017 - 02/2015
2Pain (Aches)
02/2015 - 09/2013
2Stomatitis
02/2015 - 09/2013
2Adenocarcinoma of Lung
02/2015 - 09/2013
2Exanthema (Rash)
02/2015 - 09/2013
2Cough
02/2015 - 09/2013
2Adenocarcinoma
02/2015 - 02/2014
2Acne Vulgaris
02/2015 - 09/2013
2Fatigue
02/2015 - 09/2013
1Acute Kidney Injury (Acute Renal Failure)
01/2020
1Anemia
01/2020
1Malignant Mesothelioma
01/2020
1Colorectal Neoplasms (Colorectal Cancer)
10/2019
1Asthenia
10/2019
1Alopecia (Baldness)
10/2019
1Peripheral Nervous System Diseases (PNS Diseases)
10/2019
1Arthralgia (Joint Pain)
10/2019
1Lymphoma (Lymphomas)
01/2018
1Febrile Neutropenia
01/2018
1Vision Disorders (Hemeralopia)
01/2018
1Small Cell Lung Carcinoma (Small Cell Lung Cancer)
11/2017
1Ovarian Neoplasms (Ovarian Cancer)
12/2015
1Mucositis
02/2015
1Paronychia
02/2015
1Respiratory Insufficiency (Respiratory Failure)
02/2014
1Sepsis (Septicemia)
02/2014
1Pulmonary Embolism
02/2014
1Pneumonia (Pneumonitis)
02/2014
1Dyspnea (Shortness of Breath)
09/2013

Drug/Important Bio-Agent (IBA)

5Cisplatin (Platino)FDA LinkGeneric
01/2020 - 09/2013
5Carboplatin (JM8)FDA LinkGeneric
10/2019 - 06/2014
5PlatinumIBA
11/2017 - 02/2014
4Docetaxel (Taxotere)FDA Link
10/2019 - 02/2014
4Erlotinib Hydrochloride (CP 358,774)FDA Link
01/2019 - 08/2011
4ARQ 197IBA
01/2019 - 08/2011
3ceritinibIBA
01/2022 - 01/2017
3Anaplastic Lymphoma KinaseIBA
11/2021 - 01/2017
3Tyrosine Kinase InhibitorsIBA
11/2021 - 08/2011
3Pemetrexed (MTA)FDA Link
01/2020 - 09/2013
3Paclitaxel (Taxol)FDA LinkGeneric
10/2019 - 06/2014
3AfatinibIBA
01/2018 - 09/2013
3Bevacizumab (Avastin)FDA Link
10/2014 - 02/2014
2CrizotinibIBA
11/2021 - 01/2018
2Fibroblast Growth Factors (Fibroblast Growth Factor)IBA
01/2020 - 10/2019
2LigandsIBA
01/2020 - 10/2019
2FP-1039IBA
01/2020 - 10/2019
2Retinaldehyde (Retinal)IBA
01/2020 - 10/2019
2ErbB Receptors (EGF Receptor)IBA
01/2018 - 08/2011
2nintedanibIBA
02/2015 - 02/2014
2Biomarkers (Surrogate Marker)IBA
10/2014 - 06/2014
1ensartinibIBA
11/2021
1Darbepoetin alfa (Aranesp)FDA Link
01/2020
1osimertinibIBA
01/2020
11- (1- (imidazo(1,2- a)pyridin- 6- yl)ethyl)- 6- (1- methyl- 1H- pyrazol- 4- yl)- 1H- (1,2,3)triazolo(4,5- b)pyrazineIBA
01/2020
1Antineoplastic Agents (Antineoplastics)IBA
01/2020
1binimetinibIBA
10/2019
1encorafenibIBA
10/2019
1Cetuximab (Erbitux)FDA Link
10/2019
1Proteins (Proteins, Gene)FDA Link
10/2019
1rilotumumabIBA
11/2017
1Etoposide (VP 16)FDA LinkGeneric
11/2017
1ganitumabIBA
11/2017
1Alanine Transaminase (SGPT)IBA
01/2017
1veliparibIBA
01/2017
1AZD 6244IBA
01/2017
1Melphalan (Alkeran)FDA LinkGeneric
12/2015
1Peptide Hydrolases (Proteases)FDA Link
12/2015
1Alkylating AgentsIBA
12/2015
1melflufenIBA
12/2015
1AminopeptidasesIBA
12/2015
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
06/2014
1GemcitabineFDA Link
06/2014
1NeuropilinsIBA
06/2014
1methionylmethionine (Met-Met)IBA
08/2011

Therapy/Procedure

9Drug Therapy (Chemotherapy)
01/2020 - 09/2013
6Therapeutics
10/2019 - 02/2014
1Radiotherapy
01/2022
1Duration of Therapy
01/2018
1Adjuvant Chemotherapy
01/2017
1Traditional Medicine (Folk Remedies)
04/2014
1Intravenous Infusions
02/2014